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Parnate

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Brand Name: Parnate

Generic Name: Tranylcypromine

Primary Use: Depressive states

Dosage Forms:
  • Oral tablets of 10mg
Common Side Effects:
  • Hypotension
  • Dizziness and balance disturbances
  • Insomnia or sleeplessness
  • Dry mouth
  • Urticaria
  • Constipation/ frequent loose motions
  • Anorexia
  • Blurred vision
  • Jaundice
  • Decreased libido
  • Impotence
  • Hair loss
  • Hearing loss
  • Neck stiffness
  • Loss of appetite
  • Urinary incontinence
  • Delayed ejaculation
  • Memory spasm
  • Stomach pain
  • Weight loss
  • Weakness
Moreserious side effects:
  • Hypertensive crisis with intracranial bleed
  • Angle-closure glaucoma

How long should it be taken?

The duration of treatment varies from patient to patient and doses should be tapered as per physician’s advice to prevent withdrawal effects like delirium.

Effectiveness:
  • Parnate has been proven to be efficacious in cases where other antidepressants have failed to achieve satisfactory response.
  • Not used as first line treatment due to side effects, drug interactions and dietary restriction.
 
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